November 28th, 2010

bswing

Ibogaine has helped addicts kick meth and heroin. Is it the trip that does the trick?

"Cocaine, meth, nicotine, morphine — we did the same studies with 18-MC, and it worked as well or better than ibogaine," Glick says. "We also have data that it will be useful in treating obesity. In animals, it blocks their intake of sweet and fatty foods without affecting their nutrient intake."

Glick and his cohorts have yet to determine whether their synthetic ibogaine has psychedelic properties. The rats, after all, aren't talking. "You look at an animal given ibogaine, and you can't tell if they're hallucinating. But they look positively strange," he says. "You give them 18-MC, and you can't really tell. But we hope when it gets to people, it won't produce hallucinatory effects."

Posted via email from crasch's posterous

bswing

What is the most harmful drug? - Barking up the wrong tree

The nine categories in harm to self are drug-specific mortality, drug-related mortality, drug-specific damage, drug-related damage, dependence, drug-specific impairment of mental function, drug-related impairment of mental functioning, loss of tangibles, loss of relationships, and injury. The harm to others categories are crime, environmental damage, family conflict, international damage, economic cost, and decline in community cohesion.

Overall, MCDA modelling showed alcohol was the most harmful drug (overall harm score 72), with heroin (55) and crack (54) in second and third places. Heroin, crack, and crystal meth were the most harmful drugs to the individual, whereas alcohol, heroin, and crack were the most harmful to others. The other drugs assessed followed in this order in terms of overall harm: Crystal meth (33), cocaine (27), tobacco (26), amphetamine/speed (23), cannabis (20), GHB (18), benzodiazepines (eg valium) (15), ketamine (also 15), methadone (14), mephedrone (13), butane (10), khat (9), ecstacy (9), anabolic steroids (9), LSD (7), buprenorphine (6), mushrooms (5).

Thus the new ISCD MCDA modelling showed that as well as being the most harmful drug overall, alcohol is almost three times as harmful as cocaine or tobacco. It also showed that alcohol is more than five times more harmful than mephedrone, which was recently a so-called legal high in the UK before it was made a class B controlled drug in April 2010. Ecstasy, which has had much harm-related media attention over the past two decades, is only one eighth as harmful as alcohol in this new analysis.

Posted via email from crasch's posterous