December 7th, 2003 - Open Knowledge — LiveJournal
Dec. 7th, 2003
Neuron, Vol 40, 1041-1048, 4 December 2003
Humor Modulates the Mesolimbic Reward Centers
Dean Mobbs 1,2, Michael D. Greicius 1,2,3, Eiman Abdel-Azim 1,2, Vinod Menon 1,2,4,5, and Allan L. Reiss 1,2,4,5
Humor plays an essential role in many facets of human life including psychological, social, and somatic functioning. Recently, neuroimaging has been applied to this critical human attribute, shedding light on the affective, cognitive, and motor networks involved in humor processing. To date, however, researchers have failed to demonstrate the subcortical correlates of the most fundamental feature of humor—reward. In an effort to elucidate the neurobiological substrate that subserves the reward components of humor, we undertook a high-field (3 Tesla) event-related functional MRI study. Here we demonstrate that humor modulates activity in several cortical regions, and we present new evidence that humor engages a network of subcortical regions including the nucleus accumbens, a key component of the mesolimbic dopaminergic reward system. Further, the degree of humor intensity was positively correlated with BOLD signal intensity in these regions. Together, these findings offer new insight into the neural basis of salutary aspects of humor.
03:42 pm - Are cops consitutitional?
Seton Hall Constitutional L.J. 2001, 685
ARE COPS CONSTITUTIONAL?
Police work is often lionized by jurists and scholars who claim to employ "textualist" and "originalist" methods of constitutional interpretation. Yet professional police were unknown to the United States in 1789, and first appeared in America almost a half-century after the Constitution's ratification. The Framers contemplated law enforcement as the duty of mostly private citizens, along with a few constables and sheriffs who could be called upon when necessary. This article marshals extensive historical and legal evidence to show that modern policing is in many ways inconsistent with the original intent of America's founding documents. The author argues that the growth of modern policing has substantially empowered the state in a way the Framers would regard as abhorrent to their foremost principles.
|← Previous day||(Calendar)||Next day →|